Wang N S, Knaack J
Ultrastruct Pathol. 1982 Apr-Jun;3(2):153-60. doi: 10.3109/01913128209016639.
Electron microscopic study of a case of fibromatosis hyalinica multiplex juvenilis (FHMJ) has revealed entangled tubular structures and an abundance of particles 40-60 nm in diameter in the cytoplasm, in addition to the previously described dilatation of the cisterna of endoplasmic reticulum--the "fibril-filled balls." The development of a tumor in FHMJ, therefore, involves abnormal propagation of cells, organelles, and their secretory products. The morphologic findings and the natural course of the disease suggest that this entity may be bordered between an abnormal proliferation and a true neoplasm of fibroblastlike cells.
对一例青少年多发性透明性纤维瘤病(FHMJ)的电子显微镜研究显示,除了先前描述的内质网池扩张——“充满原纤维的球”之外,细胞质中还有缠结的管状结构以及大量直径为40 - 60纳米的颗粒。因此,FHMJ中肿瘤的发生涉及细胞、细胞器及其分泌产物的异常增殖。形态学发现和疾病的自然病程表明,该实体可能介于成纤维细胞样细胞的异常增殖和真正的肿瘤之间。