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[良性乳腺疾病患者中17β-雌二醇、孕酮和糖皮质激素受体的含量]

[Content of 17 beta éstradiol, progesterone and glucocorticoid receptors in patients with benign breast diseases].

作者信息

Bassalyk L S, Kuz'mina Z V, Murav'eva N I, Smirnova K D, Vishniakova V V

出版信息

Vopr Onkol. 1982;28(7):3-6.

PMID:7101825
Abstract

The levels of estradiol-17 beta, progesterone and glucocorticoids were assayed in tumor tissues from 41 patients with benign breast tumors. Histologically, 21 tumors were identified as fibroadenomas of various types, 14--as fibrous-cystic non-proliferative mastopathy and 6--proliferative mastopathy. Tumor tissue contained estradiol receptors in 51% of cases, all three types of receptors--in 7% and none of the receptors was found in 29% of tumors. The levels of estrogen and glucocorticoids in cases of benign tumors were lower than those in cancer patients. However, in proliferative fibrous-cystic mastopathy group, estrogen receptor level was higher than in the other two groups.

摘要

对41例乳腺良性肿瘤患者的肿瘤组织进行了雌二醇-17β、孕酮和糖皮质激素水平检测。组织学检查显示,21例肿瘤为不同类型的纤维腺瘤,14例为纤维囊性非增生性乳腺病,6例为增生性乳腺病。51%的病例肿瘤组织含有雌二醇受体,7%的病例含有所有三种类型的受体,29%的肿瘤未发现任何受体。良性肿瘤患者体内雌激素和糖皮质激素水平低于癌症患者。然而,在增生性纤维囊性乳腺病组中,雌激素受体水平高于其他两组。

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