Konyshev V A
Zh Evol Biokhim Fiziol. 1982 May-Jun;18(3):296-9.
Amino acids, which synthesis was lost during animal evolution, exhibit some common physico-chemical features. These amino acids are presented by the largest molecules with the lowest density of packing of their material, the highest relative content of carbon and hydrogen, etc. It is suggested that during evolution there appeared living organisms which lacked the ability to produce various amino acids; however, natural selection fixed the loss of synthesis of only those amino acids which exhibited the above mentioned properties, as far as this loss did not interrupt vitally essential processes (glycolysis, tricarboxylic acid cycle, etc.) and did not result in elimination of these mutations. Loss of synthesis of these amino acids appeared to be favourable with respect to energy metabolism of the organism, since it made possible to "relay" some of the genes for another function.
在动物进化过程中失去合成能力的氨基酸表现出一些共同的物理化学特征。这些氨基酸由物质堆积密度最低、碳和氢相对含量最高等的最大分子呈现。有人认为，在进化过程中出现了缺乏产生各种氨基酸能力的生物体；然而，自然选择固定了仅那些具有上述特性的氨基酸合成的丧失，只要这种丧失不打断至关重要的过程（糖酵解、三羧酸循环等）且不会导致这些突变的消除。这些氨基酸合成的丧失似乎对生物体的能量代谢有利，因为这使得一些基因能够“转而”执行其他功能。
