Tsutsul'kovskaia M Ia, Mikhaĭlova V A, Izvol'skiĭ S A
Zh Nevropatol Psikhiatr Im S S Korsakova. 1982;82(5):88-98.
In 248 patients with juvenile schizophrenia lasting over 10 years since the first manifestation of the psychosis statistically significant criteria for probable prognosis of the disease outcome were determined using clinico-statistical methods. It was found that the most informative among those criteria were the characteristics of the initial stage of the disease and the premorbid period; the hereditary and genetic background, as well as the character of the disease onset and some pictures of the manifest psychosis. The criteria determined enable one to forecast with a high degree of statistical significance the intensity of the morbid process progress at the initial stages of paroxysmal schizophrenia.
对248例自首次出现精神病症状起病程持续超过10年的青少年精神分裂症患者,运用临床统计学方法确定了疾病转归可能预后的具有统计学意义的标准。结果发现,这些标准中最具信息量的是疾病初期和病前阶段的特征;遗传和基因背景,以及疾病的起病特点和明显精神病的某些表现形式。所确定的标准能够以高度的统计学意义预测阵发性精神分裂症初期病态过程进展的强度。