Sullivan J M
Acta Anat (Basel). 1982;112(2):151-7. doi: 10.1159/000145507.
Histological, histochemical fluorescence, and electron microscopic techniques have been utilized to demonstrate the specific distribution of the noradrenergic sympathetic postganglionic fibers to the guinea pig left atrium and ventricle. The majority of these nerves entered the base of the heart. Paravascular bundles of unmyelinated sympathetic postganglionic fibers traversed the left atrioventricular sulcus. From these paravascular plexuses axons accompanied the arteries via periarterial plexuses to the deeper layers of the heart wall. The vascular tree was extremely complex. In the left atrium a relatively abundant noradrenergic innervation was seen within the interstitial connective tissue surrounding the cardiac muscle. In the left ventricle, most of the noradrenergic innervation was located in the tunica adventitia of all the major coronary arterial branches before they entered the cardiac muscle. These larger branches of the coronary arteries were predominantly innervated by the sympathetic postganglionic fibers. Apparently it is from these perivascular nerve plexuses that the left ventricular muscle receives the majority of its noradrenergic innervation.
组织学、组织化学荧光和电子显微镜技术已被用于证明去甲肾上腺素能交感神经节后纤维在豚鼠左心房和心室的特定分布。这些神经大多进入心脏底部。无髓鞘交感神经节后纤维的血管旁束穿过左房室沟。从这些血管旁丛发出的轴突通过动脉周围丛伴随动脉到达心壁深层。血管树极其复杂。在左心房,在心肌周围的间质结缔组织内可见相对丰富的去甲肾上腺素能神经支配。在左心室,大部分去甲肾上腺素能神经支配位于所有主要冠状动脉分支进入心肌之前的外膜中。冠状动脉的这些较大分支主要由交感神经节后纤维支配。显然,左心室肌肉的大部分去甲肾上腺素能神经支配来自这些血管周围神经丛。