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双硫仑接受者和拒绝者:他们有差异吗?

Disulfiram acceptors and refusers: do they differ?

作者信息

O'Neil P M, Roitzsch J C, Giacinto J P, Miller W C

出版信息

Addict Behav. 1982;7(2):207-9. doi: 10.1016/0306-4603(82)90048-x.

DOI:10.1016/0306-4603(82)90048-x
PMID:7102454
Abstract

The present study examined possible personality and mood state correlates of alcoholics' decisions to accept or refuse disulfiram (Antabuse) as past of their treatment program. Subjects were 104 male veterans in an inpatient alcohol treatment program who were offered disulfiram after detoxification and evaluation. All subjects completed the Minnesota Multiphasic Personality Inventory, the Profile of Mood States, and the State-Trait Anxiety Inventory. Subjects were classified as acceptors (n = 78) or refusers (n = 26) based on their response to staff encouragement to undergo a trial of disulfiram. There were no significant group differences on age, racial composition, or any of the personality or mood state measures, with the exception of a trend (p less than .06) for acceptors to score higher than refusers on the masculinity-femininity scale of the MMPI. Examinations of distributions of MMPI profile code types similarly showed no differences between the two groups. Possible contextual explanations of these results are examined. Findings offer no support for the assumption that agreement to take disulfiram signifies greater motivation or intention to remain abstinent.

摘要

本研究调查了酗酒者决定接受或拒绝双硫仑(安塔布司)作为其治疗方案一部分时,可能与之相关的人格和情绪状态。研究对象为104名参加住院酒精治疗项目的男性退伍军人,他们在戒毒和评估后被提供了双硫仑。所有研究对象都完成了明尼苏达多相人格调查表、情绪状态剖面图和状态-特质焦虑量表。根据研究对象对工作人员鼓励其进行双硫仑试验的反应,将他们分为接受者(n = 78)或拒绝者(n = 26)。除了在明尼苏达多相人格调查表的男性化-女性化量表上,接受者得分高于拒绝者这一趋势(p < 0.06)外,两组在年龄、种族构成或任何人格或情绪状态测量方面均无显著差异。对明尼苏达多相人格调查表剖面图代码类型分布的检查同样显示,两组之间没有差异。本文探讨了这些结果可能的背景解释。研究结果不支持以下假设,即同意服用双硫仑意味着有更大的动机或意图保持戒酒。

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