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毛发神经嵴错构瘤:其与蓝色痣及马黑色素沉着病的关系。

Pilar neurocristic hamartoma: its relationship to blue nevus and equine melanotic disease.

作者信息

Tuthill R J, Clark W H, Levene A

出版信息

Arch Dermatol. 1982 Aug;118(8):592-6. doi: 10.1001/archderm.118.8.592.

DOI:10.1001/archderm.118.8.592
PMID:7103529
Abstract

A unique pigmented lesion, judged to be a hamartoma of neural crest origin, occurring in a female patient, is compared with equine melanotic disease, The characteristic perifollicular arrangement of pigment-laden spindle cells is remarkably similar in both. Previously described patch- and plaque-like blue nevi in humans are also closely related. Light and ultrastructural features showed differentiation toward both nevus cells and Schwann cells, and it is proposed that the lesion be termed pilar neurocristic hamartoma.

摘要

一名女性患者身上出现了一种独特的色素沉着病变,经判断为神经嵴起源的错构瘤,并与马黑素沉着病进行了比较。两者中充满色素的梭形细胞的特征性毛囊周围排列非常相似。先前描述的人类斑块状和斑片状蓝痣也密切相关。光镜和超微结构特征显示其向痣细胞和施万细胞分化,因此建议将该病变称为毛囊神经嵴错构瘤。

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