García Muller R, Valera M, Carrasco H, Fuenmayor A, Ramírez Benedetti J, Torrealba W, Mendoza E
Arch Inst Cardiol Mex. 1982 Mar-Apr;52(2):155-9.
The heart toxicity of N-Methyl-glucamine antimoniate (R glucantime) was studied by electrocardiographic readings in 16 patients with acute cutaneous Leishmaniasis. All patients studied came from the town of Tovar and it's surrounding areas, in the district of Tovar, Merida State, Venezuela. A dosage of 25 to 50 mg/kg/day of N-Methyl-glucamine in two or three treatment series, produced the healing of the cutaneous sore, without electrocardiographic alterations which could be interpreted as signs of myocardial toxicity.
通过心电图读数，对16例急性皮肤利什曼病患者进行了葡甲胺锑酸盐（R葡聚糖锑钠）心脏毒性研究。所有研究患者均来自委内瑞拉梅里达州托瓦尔区托瓦尔镇及其周边地区。以25至50毫克/千克/天的剂量给予葡甲胺，分两或三个疗程治疗，可使皮肤溃疡愈合，且未出现可被解释为心肌毒性迹象的心电图改变。
