Wise W J, Bakir A A, Dunea G
Arch Intern Med. 1982 Aug;142(8):1568-9.
A 46-year-old man with biopsy-proved acute tubular necrosis made a dramatic recovery after remaining oliguric and requiring maintenance hemodialysis for 11 months. The serum creatinine level declined to 5.8 mg/dL and, as hemodialysis was discontinued, a second renal biopsy showed marked regenerative changes in the renal tubules. This delayed and unexpected improvement in renal function underscores the need to avoid early renal transplantation in the patient with protracted renal failure from acute tubular necrosis.
一名经活检证实为急性肾小管坏死的46岁男性，在持续少尿并需要维持性血液透析11个月后，肾功能显著恢复。血清肌酐水平降至5.8mg/dL，随着血液透析的停止，第二次肾活检显示肾小管有明显的再生性改变。这种肾功能延迟且意外的改善强调了对于因急性肾小管坏死导致长期肾衰竭的患者，应避免早期进行肾移植。
