Brown B W, Oddy V H, Jones A W
Aust J Biol Sci. 1982;35(1):25-31.
Total uterine blood flow was measured with a tritiated water (TOH) diffusion method and with radioactive microspheres in six, conscious, pregnant ewes. With continuous infusion of TOH, equilibrium between the TOH concentration in utero-ovarian venous blood and arterial blood was attained within 50 min of the start of the infusion. The concentration of TOH in uterine and foetal tissue and in foetal blood water was the same as that in uterine venous water by 40 min; at this time, the concentration of TOH in the water of amniotic and allantoic fluids was 96% of that in uterine venous blood water. Estimates of total uterine blood flow obtained using TOH were highly correlated with those obtained with microspheres (r = 0.889, P less than 0.001, n = 8) and the corresponding mean (+/- s.e.m.) flow values obtained with the two techniques (1030.5 +/- 110.6 and 1006.2 +/- 100.0 ml min-1, respectively) did not significantly differ. The percentage of the total uterine blood flow passing through arteriovenous anastomoses ranged from 1.4 to 3.3%.
采用氚水（TOH）扩散法和放射性微球法，对6只清醒的妊娠母羊的子宫总血流量进行了测量。持续输注TOH后，子宫卵巢静脉血与动脉血中的TOH浓度在输注开始后50分钟内达到平衡。40分钟时，子宫和胎儿组织以及胎儿血液中的TOH浓度与子宫静脉水中的浓度相同；此时，羊水和尿囊液中的TOH浓度为子宫静脉血水中浓度的96%。使用TOH获得的子宫总血流量估计值与使用微球获得的估计值高度相关（r = 0.889，P < 0.001，n = 8），并且两种技术获得的相应平均（±标准误）血流量值（分别为1030.5 ± 110.6和1006.2 ± 100.0 ml min-1）无显著差异。通过动静脉吻合的子宫总血流量百分比范围为1.4%至3.3%。
