猪胃黏膜的血型（A + H）复合岩藻糖脂

Blood-group-(A + H) complex fucolipids of hog gastric mucosa.

作者信息

Slomiany B L, Slomiany A

出版信息

Eur J Biochem. 1978 Sep 15;90(1):39-49. doi: 10.1111/j.1432-1033.1978.tb12572.x.

DOI:10.1111/j.1432-1033.1978.tb12572.x

Abstract

A new group complex glycosphingolipids exhibiting blood-group-(A + H) activity was isolated from the lipid extract of hog gastric mucosa. Four components of this group have been purified to homogeneity and their structures and immunological properties were studied. The branched structures of glycolipids were identified by partial acid hydrolysis, sequential degradation with specific glycosidases, oxidation with periodate and chromium trioxide, and comparison of the permethylation products of the native and defucosylated compounds. The structures of these fucolipids are proposed to be as follows.

摘要

从猪胃黏膜的脂质提取物中分离出了一种具有血型（A + H）活性的新型复合糖鞘脂。该组的四个组分已被纯化至同质，并对其结构和免疫特性进行了研究。通过部分酸水解、用特定糖苷酶进行顺序降解、高碘酸盐和三氧化铬氧化以及比较天然化合物和去岩藻糖基化化合物的全甲基化产物，确定了糖脂的分支结构。这些岩藻糖脂的结构如下。