Gardner M J, Acheson E D, Winter P D
Br J Cancer. 1982 Jul;46(1):81-8. doi: 10.1038/bjc.1982.168.
The geographical distribution of mortality from mesothelioma of the pleura during the years 1968-78 in England and Wales has been studied using extracts from the death records held by the Office of Population Censuses and Surveys. Using the national death rate as standard, Local Authority areas with raised mortality are identified. The patterns are somewhat different for each sex. In men the high-mortality areas are mainly the major ports where shipbuilding and repairing have been concentrated, whereas in women areas where gas masks are manufactured are predominant. In both sexes there are also high death rates on the eastern side of London. Nearly all the areas of high mortality are known to have had a major asbestos-using industry in the past. Over the 11-year period the annual number of deaths from pleural mesothelioma rose by approximately 75%. This marked increase was virtually confined to men, in whom the number of deaths had reached almost 200 per annum by 1978. The indications are that the effect of past high exposures, in particular to amphibole asbestos, have not yet reached a peak in terms of mortality. On the other hand imports and usage of amphiboles, particularly crocidolite, have decreased rapidly since the mid-1960s, and dust levels in the working environment have improved even more radically.
利用人口普查与调查办公室保存的死亡记录摘录,对1968年至1978年间英格兰和威尔士胸膜间皮瘤死亡率的地理分布进行了研究。以全国死亡率为标准,确定了死亡率升高的地方当局区域。男女的模式略有不同。在男性中,高死亡率地区主要是造船和修船集中的主要港口,而在女性中,主要是生产防毒面具的地区。在男女中,伦敦东部的死亡率也很高。几乎所有高死亡率地区过去都有一个主要的石棉使用行业。在这11年期间,胸膜间皮瘤的年死亡人数增加了约75%。这种显著增加几乎仅限于男性,到1978年,男性的死亡人数已达到每年近200人。有迹象表明,过去高暴露,特别是接触闪石石棉的影响,在死亡率方面尚未达到峰值。另一方面,自20世纪60年代中期以来,闪石,特别是青石棉的进口和使用迅速减少,工作环境中的粉尘水平改善更为显著。