Halliday B L
Br J Ophthalmol. 1982 Aug;66(8):477-91. doi: 10.1136/bjo.66.8.477.
Decreased contrast sensitivity has been demonstrated in early glaucoma, but the deficit in not regularly observed. We designed a prototype for a forced-choice printed test and evaluated it with several other measures of contrast sensitivity. The results also bear on the pattern of loss and the variables which effect performance. Mildly glaucomatous patients show at 6 db (50%) loss of contrast sensitivity at all spatial frequencies tested compared with age matched controls. Moving gratings give the same information as stationary ones, and practice effects are negligible. Contrast sensitivity at or below 2 cycles/degree is poorly correlated with visual acuity and does not change with age in the forced-choice test. Subjective judgment made the apparent contrast threshold higher, age dependent, and more variable, particularly at higher spatial frequencies. The pattern of variability can explain some reports of insignificant effects and why low spatial frequency contrast sensitivity detects glaucoma better than visual acuity. Methods correlated so poorly, despite high reliabilities, that uncontrolled biases must be suspected in subjective measures. Our new forced-choice format was superior to all other tests on at least one formal criterion and always at least equal to them. Improvements in contrast sensitivity screening tests are thus indicated.
早期青光眼患者已被证实存在对比敏感度下降的情况,但这种缺陷并非经常被观察到。我们设计了一种用于强制选择印刷测试的原型,并将其与其他几种对比敏感度测量方法一起进行了评估。结果还与损失模式以及影响表现的变量有关。与年龄匹配的对照组相比,轻度青光眼患者在所有测试空间频率下,对比敏感度均有6分贝(50%)的损失。移动光栅与静止光栅提供相同的信息,练习效应可忽略不计。在强制选择测试中,2周期/度及以下的对比敏感度与视力的相关性较差,且不随年龄变化。主观判断使明显的对比阈值更高、与年龄相关且更具变异性,尤其是在较高空间频率时。变异性模式可以解释一些关于影响不显著的报告,以及为什么低空间频率对比敏感度比视力更能检测出青光眼。尽管可靠性很高,但方法之间的相关性很差,因此必须怀疑主观测量中存在未控制的偏差。我们新的强制选择形式在至少一个正式标准上优于所有其他测试,并且总是至少与它们相当。因此,有必要改进对比敏感度筛查测试。