慢波睡眠期间脉络丛中的葡萄糖利用率增加。一项对猫进行的[14C]脱氧葡萄糖研究。
Glucose utilization increases in choroid plexus during slow wave sleep. A [14C] deoxyglucose study in the cat.
作者信息
Bobillier P, Seguin S, Petitjean F, Buda C, Salvert D, Janin M, Chouvet G, Jouvet M, Des Rosiers M H
出版信息
Brain Res. 1982 May 27;240(2):359-63. doi: 10.1016/0006-8993(82)90237-2.
PMID:7104698
Abstract
Glucose utilization (GU) was measured during spontaneous waking and slow-wave sleep (SWS) by adaptation of the [14C]deoxyglucose method to the unrestrained cat. In sleeping animals a greater autoradiographic signal between choroid plexus (CP) and the rest of brain was noticed. Quantification provided an index of the metabolic rate of CP and confirmed that mean values for GU were significantly higher in "sleeping' than in "awake' cats.
摘要
通过将[14C]脱氧葡萄糖法应用于自由活动的猫，测量了自发清醒和慢波睡眠（SWS）期间的葡萄糖利用率（GU）。在睡眠动物中，脉络丛（CP）与大脑其他部位之间的放射自显影信号更强。定量分析提供了脉络丛代谢率的指标，并证实“睡眠”猫的GU平均值显著高于“清醒”猫。
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