弗里德赖希共济失调中α-酮酸的定量代谢谱分析
Quantitative metabolic profiling of alpha-keto acids in Friedreich's ataxia.
作者信息
Bertrand M J, Bouchard R, Gauthier G L, Bouchard J P, Barbeau A
出版信息
Can J Neurol Sci. 1982 May;9(2):231-4. doi: 10.1017/s0317167100044012.
PMID:7104888
Abstract
The plasma distribution of alpha-keto acids was measured in 26 subjects including 8 patients with Friedreich's ataxia, 8 with the recessive spastic ataxia of Charlevoix-Sageunay and 10 healthy volunteers. The groups were matched with regards to age, sex, weight and the study was conducted under standardized dietary intake. The result indicate significant differences in the alpha-keto acids distribution between the groups.
摘要
在26名受试者中测量了α-酮酸的血浆分布情况，其中包括8名弗里德赖希共济失调患者、8名夏尔沃-萨格奈隐性痉挛性共济失调患者和10名健康志愿者。这些组在年龄、性别、体重方面相匹配，并且该研究是在标准化饮食摄入情况下进行的。结果表明各组之间α-酮酸分布存在显著差异。
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