Rasmussen A, Hessov I, Bojsen-Møller M
Infusionsther Klin Ernahr. 1982 Jun;9(3):117-9. doi: 10.1159/000221335.
The object of this study was to show (A) whether the transient fall in plasma phosphate during carbohydrate infusions could be prevented by adding 10 mmol phosphorus to 1 litre of 10% glucose solution, (B) whether this unphysiologically high concentration would change the vein damaging properties of the acid sugar solution, when the phosphorus was added as a phosphate buffer. Study A comprised 16 patients undergoing colonic surgery. On the second postoperative day the patients received 1 litre 10% glucose, half of the solutions were added 10 mmol phosphate buffer. Plasma phosphate dropped during the infusion in all the patients in the unsubstituted group, whereas there was no fall in the phosphate substituted group. The difference between the two groups was significant. Study B comprised 23 rabbits. Sequential analysis demonstrated that the phosphate addition did not change the vein damaging properties of a 10% glucose solution.
（A）在1升10%葡萄糖溶液中添加10毫摩尔磷是否能防止碳水化合物输注期间血浆磷酸盐的短暂下降；（B）当磷作为磷酸盐缓冲液添加时，这种非生理性的高浓度是否会改变酸性糖溶液的静脉损伤特性。研究A包括16例接受结肠手术的患者。术后第二天，患者接受1升10%葡萄糖，其中一半溶液添加10毫摩尔磷酸盐缓冲液。未添加组的所有患者在输注期间血浆磷酸盐均下降，而添加磷酸盐组则没有下降。两组之间的差异具有显著性。研究B包括23只兔子。序贯分析表明，添加磷酸盐不会改变10%葡萄糖溶液的静脉损伤特性。
