Guillou P J, Morgan D B, Hill G L
Lancet. 1976 Oct 2;2(7988):710-2. doi: 10.1016/s0140-6736(76)90007-6.
Plasma and urinary phosphate levels were studied before and after operation in 13 patients undergoing uncomplicated major surgery. The maintenance intravenous fluid in six patients was 0.9% saline and in the other seven patients it was 4% dextrose with 0.18% saline. Although the plasma-phosphate fell in both groups, reaching minimum on the second postoperative day and then returning towards normal, it was significantly lower in the group receiving dextrose on the second, third, and fourth postoperative days when the levels were below the normal range. It is suggested that when dextrose-saline solutions are indicated in postoperative patients the addition of phosphate to the solution should be considered.
对13例接受非复杂性大手术的患者在手术前后的血浆和尿磷水平进行了研究。6例患者的维持静脉输液为0.9%生理盐水,另外7例患者的维持静脉输液为含0.18%生理盐水的4%葡萄糖溶液。虽然两组患者的血浆磷均下降,在术后第二天降至最低,然后恢复正常,但在术后第二、第三和第四天,接受葡萄糖溶液组的血浆磷显著低于正常范围。建议当术后患者需要使用葡萄糖盐溶液时,应考虑在溶液中添加磷酸盐。