Barb W, Park J B, Kenner G H, von Recum A F
J Biomed Mater Res. 1982 Jul;16(4):447-58. doi: 10.1002/jbm.820160412.
In order to minimize the problems associated with implant fixation using acrylic bone cement, a new technique has been investigated. Canine hip prostheses were precoated with self-curing acrylic bone cement and implanted in random source dogs using the same cement for fixation, a precoated prosthesis on one side and an uncoated (control) on the other. After 1, 3, and 6 months, both femora were excised and sectioned for mechanical assessment of the interfaces among bone, cement, and implant. It was found that the precoated implants had much higher interfacial shear strengths than the uncoated ones (average 14.2 and 6.8 MPa for implant-cement interface; 2.0 and 1.2 MPa for the cement-bone interface for all implant periods). The precoated "old" cement and the "new" cement's interfacial shear strength was the strongest with an average of 15.1 MPa for all implant periods. The present results indicate that the precoated hemiarthroplastic implants provide a firmer intramedullary fixation than the traditional, uncoated implants.
为了尽量减少使用丙烯酸骨水泥进行植入物固定相关的问题,人们研究了一种新技术。犬髋关节假体预先涂覆自固化丙烯酸骨水泥,并使用相同的水泥植入随机选取的犬只体内进行固定,一侧为预涂覆假体,另一侧为未涂覆(对照)假体。在1、3和6个月后,切除两侧股骨并进行切片,以对骨、水泥和植入物之间的界面进行力学评估。结果发现,预涂覆植入物的界面剪切强度比未涂覆植入物高得多(在所有植入时间段内,植入物 - 水泥界面的平均剪切强度分别为14.2和6.8 MPa;水泥 - 骨界面的平均剪切强度分别为2.0和1.2 MPa)。预涂覆的“旧”水泥和“新”水泥的界面剪切强度最强,在所有植入时间段内平均为15.1 MPa。目前的结果表明,预涂覆半关节置换植入物比传统的未涂覆植入物提供更牢固的髓内固定。