Dore B, Dombriz M, Denis P, Darracq-Paries J C, Barbier J, Aubert J
J Urol (Paris). 1982;88(4):247-52.
The authors, after personally observing three cases, review the literature on breast cancers in patients with prostatic cancer treated by estrogens. The authors' three cases are all metastatic breast cancers, and one has also a renal cancer. These three cases are added to the 22 reported in the literature which include 13 metastatic cancers, 6 primary breast cancers, and 3 cancers of unspecified nature. The seriousness of these breast involvements is obvious when they are a manifestation of tumor dissemination. The authors discuss the possible responsibility of the estrogen therapy in the development of the breast cancer. The downhill course and the appearance of breast cancer with generalized dissemination evinces an important decrease in the patient's immunity which allows metastases and multiple tumors to occur.
作者在亲自观察了三例病例后，回顾了有关接受雌激素治疗的前列腺癌患者发生乳腺癌的文献。作者的三例病例均为转移性乳腺癌，其中一例还患有肾癌。这三例病例被添加到文献报道的22例中，其中包括13例转移性癌、6例原发性乳腺癌和3例性质未明的癌症。当这些乳腺受累是肿瘤播散的表现时，其严重性显而易见。作者讨论了雌激素治疗在乳腺癌发生中的可能作用。病情的恶化以及伴有广泛播散的乳腺癌的出现表明患者免疫力显著下降，从而导致转移和多发性肿瘤的发生。
