Schwab W E, Josephson R K
J Exp Biol. 1982 Jun;98:175-93. doi: 10.1242/jeb.98.1.175.
Conduction velocity lability was studied in the electrically excitable epithelium of Euphysa japonica by means of intracellular recordings. Three classes of response latency change were identified in response to bursts of stimuli: an initial jump, uniform drift and abrupt jumps in latency. In each case an increase in stimulus frequency produced an increase in latency. The initial jump in latency, which occurred between the first and second response of a series, was related to the afterpotential of the first response. The increased latency of the second response appears to result from the drop in membrane resistance during the hyperpolarizing afterpotential. The uniform drift in latency remains unexplained but may be the result of ion accumulation within the tissue, progressive inactivation of the ionic channels involved in producing the action potential, or junctional phenomena. The abrupt jumps in latency, which often preceded failure to respond, were found to be impulse initiation phenomena.
通过细胞内记录法研究了日本真枝螅电兴奋性上皮组织中的传导速度不稳定性。在对刺激脉冲的反应中识别出了三类反应潜伏期变化：初始跃变、均匀漂移和潜伏期的突然跃变。在每种情况下，刺激频率的增加都会导致潜伏期增加。潜伏期的初始跃变出现在一系列反应的第一个和第二个反应之间，与第一个反应的后电位有关。第二个反应潜伏期的增加似乎是由于超极化后电位期间膜电阻的下降。潜伏期的均匀漂移原因尚不清楚，但可能是组织内离子积累、产生动作电位所涉及的离子通道逐渐失活或连接现象的结果。潜伏期的突然跃变通常发生在反应失败之前，被发现是冲动起始现象。
