膳食磷脂及其组成碱基对大鼠血清脂质和载脂蛋白的影响。
Effect of dietary phospholipids and their constituent bases on serum lipids and apolipoproteins in rats.
作者信息
Murata M, Imaizumi K, Sugano M
出版信息
J Nutr. 1982 Sep;112(9):1805-8. doi: 10.1093/jn/112.9.1805.
To evaluate alterations of serum lipoproteins, liver lipids and fecal sterol excretion caused by feeding a crude soybean phospholipid preparation, the effect of purified phospholipids and phospholipid bases were studied in rats. Soybean phosphatidylcholine preparations showed no effect on serum lipoproteins and liver lipids. Egg yolk phospholipid, which contained phosphatidylethanolamine and phosphatidylcholine, caused a decrease in serum cholesterol and apoprotein A-I and an increase in serum apoprotein B and liver cholesterol. Ethanolamine, but not choline and inositol, showed an effect on serum lipoproteins similar to egg yolk phospholipid. All phospholipids tested increased fecal excretion of neutral sterols. It is suggested that phosphatidylethanolamine exerts marked influence on serum lipoprotein levels.
为评估喂食粗制大豆磷脂制剂引起的血清脂蛋白、肝脏脂质和粪便固醇排泄的变化，研究了纯化磷脂和磷脂碱对大鼠的影响。大豆磷脂酰胆碱制剂对血清脂蛋白和肝脏脂质无影响。含有磷脂酰乙醇胺和磷脂酰胆碱的蛋黄磷脂可使血清胆固醇和载脂蛋白A-I降低，血清载脂蛋白B和肝脏胆固醇升高。乙醇胺而非胆碱和肌醇，对血清脂蛋白的影响与蛋黄磷脂相似。所有测试的磷脂均增加了中性固醇的粪便排泄。提示磷脂酰乙醇胺对血清脂蛋白水平有显著影响。
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