McCarron J P, Chasko S B, Gray G F
J Urol. 1982 Aug;128(2):243-6. doi: 10.1016/s0022-5347(17)52871-2.
The nature and extent of mucosal alterations in 30 consecutive surgical specimens removed for urothelial neoplasia were evaluated by systematic mapping. The findings correlated with pertinent pathological, cytological and clinical data. Generally, the grade of the principal neoplasm paralleled the degree of epithelial disturbance in the grossly normal urothelium, high grade carcinomas being associated consistently with severe changes and low grade cancers with hyperplasia only. Cytological studies reflected accurately the grade of the principal neoplasm, and the presence of concomitant contiguous and remote mucosal abnormalities.
通过系统绘图评估了连续30例因尿路上皮肿瘤而切除的手术标本中黏膜改变的性质和范围。研究结果与相关的病理、细胞学和临床数据相关。一般来说，主要肿瘤的分级与大体正常尿路上皮中的上皮紊乱程度平行，高级别癌始终与严重改变相关，低级别癌仅与增生相关。细胞学研究准确反映了主要肿瘤的分级，以及同时存在的相邻和远处黏膜异常情况。
