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[缺血性心脏病中心肌收缩能力取决于冠状动脉粥样硬化程度及左心室壁运动不协调的存在情况]

[Myocardial contractile capacity in ischemic heart disease depending on the degree of coronary arteriosclerosis and the presence of parietal asynergy of the left ventricle].

作者信息

Sokolov Iu N, Kuchuk A A

出版信息

Kardiologiia. 1982;22(7):48-51.

PMID:7109448
Abstract

Myocardial contractility was studied in 44 patients with ischaemic heart disease (28 with asynergy) without congestive circulatory insufficiency depending on the degree of coronary atherosclerosis and regional disorder in the movement of the wall of the left ventricle by ventriculography and tensiometry (dp/dt max, Veraguth index, VCE40; t-dp/dt max). No dependence was detected between the growth of the total lesions of cardiac arteries and the increase of the end diastolic and end systolic volumes and the fall of the ejection fraction in patients with normokinesia of the left ventricle. However, a strong inverse relationship has been established between the number of the affected segments of the heart and the ejection fraction (r = -0.90). It was shown that indices of contractility reflecting the pre-ejection phase (dp/dt max, Veraguth index VCE40; t-dp/ max) are less sensitive in determining the cardiac insufficiency than Vcf and must be interpreted simultaneously with the results of the regional contractility according to the ventriculography data.

摘要

对44例缺血性心脏病患者(其中28例有心肌运动不协调)且无充血性循环功能不全的患者,根据冠状动脉粥样硬化程度以及通过心室造影和张力测量法(dp/dt max、韦拉古特指数、VCE40;t-dp/dt max)测定的左心室壁运动的局部紊乱情况,研究心肌收缩力。在左心室运动正常的患者中,未发现心脏动脉总病变的增加与舒张末期和收缩末期容积的增加以及射血分数的降低之间存在相关性。然而,已确定心脏受累节段的数量与射血分数之间存在强烈的负相关(r = -0.90)。结果表明,反映射血前期的收缩力指标(dp/dt max、韦拉古特指数VCE40;t-dp/dt max)在确定心功能不全方面不如Vcf敏感,必须根据心室造影数据与局部收缩力的结果同时进行解读。

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