Mikkelsen O A
Hand. 1978 Feb;10(1):1-8. doi: 10.1016/s0072-968x(78)80019-9.
The influence of handedness, work and previous hand trauma is studied in 901 persons with Dupuytren's disease, collected in an epidemiological study of 15,950 citizens in a small, Norwegian town. Dupuytren's disease occurred in all occupational groups, but the prevalence was higher and the contracture more severe in people doing hard manual work than in people doing light or non manual work. Persons with Dupuytren's disease has sustained previous hand trauma more frequently than the general population, and the interval between trauma and first sign of disease was usually a few years. Previous hand injuries were definitely more common among people doing hard manual work, but even when these were excluded from the work material, Dupuytren's disease was still more common among people doing hard manual work, than in people doing light or non manual work. The study has indicated that Dupuytren's disease in certain cases is precipitated and/or aggravated by both work and definite hand injury.
在对挪威一个小镇15950名居民进行的流行病学研究中,收集了901例患有杜普伊特伦挛缩症的患者,研究了用手习惯、工作及既往手部创伤对该病的影响。杜普伊特伦挛缩症在所有职业群体中均有发生,但从事重体力劳动的人群中该病的患病率更高,挛缩也比从事轻体力劳动或非体力劳动的人群更为严重。患有杜普伊特伦挛缩症的患者比普通人群更频繁地遭受过既往手部创伤,创伤与疾病首发症状之间的间隔通常为数年。既往手部损伤在从事重体力劳动的人群中肯定更为常见,但即使将这些人群排除在研究资料之外,从事重体力劳动的人群中杜普伊特伦挛缩症仍比从事轻体力劳动或非体力劳动的人群更为常见。该研究表明,在某些情况下,工作和明确的手部损伤会促使和/或加重杜普伊特伦挛缩症。