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[门诊护理中随访的胰岛素依赖型糖尿病患者血红蛋白A1与其他代谢及临床参数的相关性]

[Correlations between hemoglobin A1 and other metabolic and clinical parameters in insulin-dependent diabetics followed in ambulatory care].

作者信息

Moratti F, Bielli L, Ferrè A, Birocchi D

出版信息

Minerva Med. 1982 Sep 15;73(35):2269-73.

PMID:7110604
Abstract

210 HbA1 percentage tests were determined in 52 ambulatory insulinodependent patients. There was a close correlation between HbA1 and blood-glucose of the previous two months: mean post-prandial, mean daily and, less strongly, mean fasting blood-glucose. The level of glycosylated haemoglobins correlated significantly with blood-glucose of the same time and highly with mean 24 hour glycosuria 0/00 of previous two months. There was also a slight inverse correlation between HbA1 and uricemia. No correlation resulted with total lipemia, serum triglyceride levels, serum total cholesterol levels and HDL cholesterol concentrations. The increased proportions of HbA1 did not not appear to be related to the age of the patients or to the duration of diabetes or to complications. HbA1 measurement is a simple and objective test of metabolic control in diabetic subjects.

摘要

对52名门诊胰岛素依赖型患者进行了210次糖化血红蛋白(HbA1)百分比检测。HbA1与前两个月的血糖之间存在密切相关性:餐后平均血糖、每日平均血糖,以及相关性稍弱的空腹平均血糖。糖化血红蛋白水平与同期血糖显著相关,与前两个月24小时尿糖平均水平(千分比)高度相关。HbA1与血尿酸之间也存在轻微的负相关。与总血脂、血清甘油三酯水平、血清总胆固醇水平及高密度脂蛋白胆固醇浓度无相关性。HbA1比例升高似乎与患者年龄、糖尿病病程或并发症无关。HbA1检测是糖尿病患者代谢控制的一项简单而客观的检测方法。

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