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意大利和瑞士学童的脂质、脂蛋白以及载脂蛋白A和载脂蛋白B的脂蛋白分布。日内瓦调查

Lipid, lipoprotein and APO-A and APO-B lipoprotein distribution in Italian and Swiss schoolchildren. The Geneva survey.

作者信息

Oberhänsli I, Pometta D, Micheli H, Raymond L, Suenram A

出版信息

Pediatr Res. 1982 Aug;16(8):665-9. doi: 10.1203/00006450-198208000-00016.

Abstract

Cholesterol and triglyceride lipid, lipoprotein as well as apolipoprotein A and B levels, are presented for Italian and Swiss schoolchildren of similar socio-economic origin, living in Geneva, and ranging in age from 8-9 and 14-15 years. This cross-sectional study revealed some differences associated with the ethnic origin of the participants. Furthermore subtle changes were related to age, associated with puberty and were sex-specific. Apolipoprotein A and B levels were found to be significantly related to age and less significantly to sex, whereas apolipoprotein A levels decrease with puberty, apolipoprotein B levels increase slightly. Of the 387 Italian and the 416 Swiss participants, 173 Italian and 193 Swiss children had a complete lipoprotein examination including apolipoprotein determination, whereas serum cholesterol and serum triglycerides were studied in the total group.

摘要

针对生活在日内瓦、社会经济背景相似、年龄在8至9岁以及14至15岁之间的意大利和瑞士学童,给出了胆固醇、甘油三酯脂质、脂蛋白以及载脂蛋白A和B的水平。这项横断面研究揭示了一些与参与者种族起源相关的差异。此外,细微变化与年龄有关,与青春期相关且具有性别特异性。发现载脂蛋白A和B水平与年龄显著相关,与性别相关性较小,而载脂蛋白A水平随青春期下降,载脂蛋白B水平略有上升。在387名意大利参与者和416名瑞士参与者中,173名意大利儿童和193名瑞士儿童进行了包括载脂蛋白测定在内的完整脂蛋白检查,而对整个群体研究了血清胆固醇和血清甘油三酯。

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