Willer J C
Nouv Presse Med. 1982 Jun 12;11(28):2125-9.
The demonstration of a close relationship between the threshold of nociceptive flexion reflexes and that of the painful sensation resulting from stimulation of the sural nerve or of the corresponding skin territory has made it possible to devise a method for objective measurement of pain in man. The method can be of interest to locate with accuracy the site of action of certain drugs and to determine the intensity of their analgesic effect. The results obtained with non-narcotic analgesics are presented.
伤害性屈曲反射阈值与腓肠神经或相应皮肤区域刺激所产生的疼痛感觉阈值之间存在密切关系，这一发现使得设计一种客观测量人类疼痛的方法成为可能。该方法对于精确确定某些药物的作用部位以及测定其镇痛效果的强度可能具有重要意义。文中给出了使用非麻醉性镇痛药所获得的结果。
