Ambrosch F, Wiedermann G, Krepler P, Kundi M
Fortschr Med. 1978 Nov 23;96(44):2231-4, 2242.
The possible influence of BCG vaccination on leukemia mortality of infants was investigated by various authors. The methods used were prospective trials, retrospective studies and epidemiological analyses. In some of these studies a protective effect of BCG vaccination was observed, in other studies no influence was found. Up to now this problem is subject to controversial discussions. An epidemiological analysis of the Austrian data using trend analyses, regression analyses and analyses of rank correlation showed an inverse correlation between BCG vaccination rate of newborns and leukemia mortality in the age group 0--5 years. From this correlation a protection rate of 0.77 could be calculated.
多位作者研究了卡介苗接种对婴儿白血病死亡率的可能影响。所采用的方法有前瞻性试验、回顾性研究和流行病学分析。在其中一些研究中观察到卡介苗接种的保护作用，而在其他研究中未发现有影响。到目前为止，这个问题仍存在争议性的讨论。利用趋势分析、回归分析和等级相关分析对奥地利的数据进行的流行病学分析表明，新生儿卡介苗接种率与0至5岁年龄组的白血病死亡率之间呈负相关。根据这种相关性可以计算出保护率为0.77。
