Zelenka P S, Beebe D C, Feagans D E
Science. 1982 Sep 24;217(4566):1265-7. doi: 10.1126/science.7112130.
Agents that induce differentiation of lens epithelial cells into lens fiber cells in vitro transiently stimulate the transmethylation of phosphatidylethanolamine. Inhibition of transmethylation by 3-deazaadenosine results in a corresponding inhibition of the cell elongation that characterizes lens fiber formation, suggesting that phospholipid methylation plays an essential role in the differentiation of these cells.
在体外诱导晶状体上皮细胞分化为晶状体纤维细胞的试剂会短暂刺激磷脂酰乙醇胺的转甲基作用。3-去氮腺苷对转甲基作用的抑制会相应地抑制以晶状体纤维形成为特征的细胞伸长，这表明磷脂甲基化在这些细胞的分化中起重要作用。
