3-去氮腺苷对磷脂酰乙醇胺N-甲基化的抑制作用通过CDP-胆碱途径刺激磷脂酰胆碱的合成。 - Suppr

Suppr

超能文献

Inhibition of phosphatidylethanolamine N-methylation by 3-deazaadenosine stimulates the synthesis of phosphatidylcholine via the CDP-choline pathway.

作者信息

Pritchard P H, Chiang P K, Cantoni G L, Vance D E

出版信息

J Biol Chem. 1982 Jun 10;257(11):6362-7.

PMID:7076675

Abstract

摘要

相似文献

Inhibition of phosphatidylethanolamine N-methylation by 3-deazaadenosine stimulates the synthesis of phosphatidylcholine via the CDP-choline pathway.3-去氮腺苷对磷脂酰乙醇胺N-甲基化的抑制作用通过CDP-胆碱途径刺激磷脂酰胆碱的合成。

J Biol Chem. 1982 Jun 10;257(11):6362-7.

The biosynthesis of phosphatidylcholine by methylation of phosphatidylethanolamine derived from ethanolamine is not required for lipoprotein secretion by cultured rat hepatocytes.由乙醇胺衍生的磷脂酰乙醇胺甲基化生成磷脂酰胆碱的生物合成过程，对于培养的大鼠肝细胞分泌脂蛋白而言并非必需。

Biochim Biophys Acta. 1986 Feb 28;875(3):501-9. doi: 10.1016/0005-2760(86)90070-6.

A deazaadenosine-insensitive methylation of phosphatidylethanolamine is involved in lipoprotein secretion.磷脂酰乙醇胺的一种对脱氮腺苷不敏感的甲基化参与脂蛋白分泌。

FEBS Lett. 1986 Aug 18;204(2):243-6. doi: 10.1016/0014-5793(86)80820-1.

Glucagon inhibits phosphatidylcholine biosynthesis via the CDP-choline and transmethylation pathways in cultured rat hepatocytes.胰高血糖素通过CDP-胆碱和转甲基化途径抑制培养的大鼠肝细胞中磷脂酰胆碱的生物合成。

Can J Biochem Cell Biol. 1984 Apr;62(4):196-202. doi: 10.1139/o84-028.

Phosphatidylcholine synthesis in yeast.酵母中的磷脂酰胆碱合成

J Lipid Res. 1988 Jan;29(1):9-14.

Regulation of phospholipid biosynthesis in isolated rat hepatocytes. Effect of different substrates.离体大鼠肝细胞中磷脂生物合成的调节。不同底物的作用。

J Biol Chem. 1975 May 10;250(9):3359-67.

Phospholipids biosynthesis by methylations and choline incorporation: effect of 3-deazaadenosine.

Biochem Biophys Res Commun. 1980 May 14;94(1):174-81. doi: 10.1016/s0006-291x(80)80203-8.

Expression of phosphatidylethanolamine N-methyltransferase-2 in McArdle-RH7777 hepatoma cells inhibits the CDP-choline pathway for phosphatidylcholine biosynthesis via decreased gene expression of CTP:phosphocholine cytidylyltransferase.磷脂酰乙醇胺N-甲基转移酶-2在McArdle-RH7777肝癌细胞中的表达通过降低CTP：磷酸胆碱胞苷转移酶的基因表达来抑制磷脂酰胆碱生物合成的CDP-胆碱途径。

Biochem J. 1995 Dec 15;312 ( Pt 3)(Pt 3):939-45. doi: 10.1042/bj3120939.

Effect of the methylation inhibitors 3-deazaadenosine and 3-deazaaristeromycin on phosphatidylcholine formation in Tetrahymena.甲基化抑制剂3-脱氮腺苷和3-脱氮杀结核菌素对四膜虫中磷脂酰胆碱形成的影响。

Biochim Biophys Acta. 1990 Dec 4;1047(3):290-3. doi: 10.1016/0005-2760(90)90528-6.

Expression of phosphatidylethanolamine N-methyltransferase-2 cannot compensate for an impaired CDP-choline pathway in mutant Chinese hamster ovary cells.磷脂酰乙醇胺N-甲基转移酶-2的表达无法弥补突变型中国仓鼠卵巢细胞中受损的CDP-胆碱途径。

J Biol Chem. 1995 Jul 7;270(27):16277-82. doi: 10.1074/jbc.270.27.16277.

引用本文的文献

Biochemistry and Diseases Related to the Interconversion of Phosphatidylcholine, Phosphatidylethanolamine, and Phosphatidylserine.生物化学与磷脂酰胆碱、磷脂酰乙醇胺和磷脂酰丝氨酸相互转化相关的疾病。

Int J Mol Sci. 2024 Oct 6;25(19):10745. doi: 10.3390/ijms251910745.

Phosphocholine cytidylyltransferase MoPct1 is crucial for vegetative growth, conidiation, and appressorium-mediated plant infection by .磷酸胆碱胞苷转移酶MoPct1对于营养生长、分生孢子形成以及由……介导的附着胞介导的植物感染至关重要。

Front Microbiol. 2023 May 5;14:1136168. doi: 10.3389/fmicb.2023.1136168. eCollection 2023.

Phosphatidylethanolamine homeostasis under conditions of impaired CDP-ethanolamine pathway or phosphatidylserine decarboxylation.在CDP-乙醇胺途径受损或磷脂酰丝氨酸脱羧的情况下，磷脂酰乙醇胺的稳态。

Front Nutr. 2023 Jan 5;9:1094273. doi: 10.3389/fnut.2022.1094273. eCollection 2022.

Biosynthesis of diacylglyceryl-N,N,N-trimethylhomoserine in Rhodobacter sphaeroides and evidence for lipid-linked N methylation.球形红细菌中二酰甘油-N,N,N-三甲基高丝氨酸的生物合成及脂质连接的N-甲基化证据。

J Bacteriol. 1996 Nov;178(21):6140-4. doi: 10.1128/jb.178.21.6140-6144.1996.

Biochem J. 1995 Dec 15;312 ( Pt 3)(Pt 3):939-45. doi: 10.1042/bj3120939.

Evidence that binding of CTP:phosphocholine cytidylyltransferase to membranes in rat hepatocytes is modulated by the ratio of bilayer- to non-bilayer-forming lipids.CTP：磷酸胆碱胞苷转移酶与大鼠肝细胞中膜的结合受双层形成脂质与非双层形成脂质比例调节的证据。

Biochem J. 1993 Apr 15;291 ( Pt 2)(Pt 2):419-27. doi: 10.1042/bj2910419.

Modulation of phosphatidylcholine biosynthesis by peroxisome proliferating fatty acid analogues.过氧化物酶体增殖性脂肪酸类似物对磷脂酰胆碱生物合成的调节

Lipids. 1993 Sep;28(9):795-801. doi: 10.1007/BF02536233.

Insulin stimulation of phospholipid methylation in isolated rat adipocyte plasma membranes.胰岛素对分离的大鼠脂肪细胞质膜中磷脂甲基化的刺激作用。

Proc Natl Acad Sci U S A. 1984 Feb;81(4):1089-92. doi: 10.1073/pnas.81.4.1089.

Beta-adrenergic control of phosphatidylcholine synthesis by transmethylation in hepatocytes from juvenile, adult and adrenalectomized rats.幼年、成年和肾上腺切除大鼠肝细胞中通过转甲基作用对磷脂酰胆碱合成的β-肾上腺素能控制

Biochem J. 1983 Dec 15;216(3):675-80. doi: 10.1042/bj2160675.

Fatty acids reverse the cyclic AMP inhibition of triacylglycerol and phosphatidylcholine synthesis in rat hepatocytes.脂肪酸可逆转环磷酸腺苷对大鼠肝细胞中三酰甘油和磷脂酰胆碱合成的抑制作用。

Biochem J. 1983 Oct 15;216(1):129-36. doi: 10.1042/bj2160129.

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