Lemer J, Malberger E, König-Nativ R
Thorax. 1982 Apr;37(4):270-4. doi: 10.1136/thx.37.4.270.
In a pilot study, 21 patients underwent transbronchial fine needle aspiration (TBFNA) using a 45 cm-22 gauge needle guided by means of a semi-rigid metal sleeve, which was introduced through a standard rigid bronchoscope. A total of 33 aspirations were performed from main carina (15), paratracheal (five), and lobar carinal (13) foci. Six aspirations yielded malignant cellular samples, 22 aspirations presented only normal cells, and in five no adequate cellular sample was obtained. Fifteen patients underwent surgical exploration (mediastinoscopy with or without thoracotomy). Four of the cytologically malignant cases were explored and in three the aspiration site was confirmed histologically. In the remaining patients where the site of aspiration was explored, no tumour was demonstrated in the cytologically negative or cytologically inadequate cases. There were no complications from TBFNA. We suggest that TBFNA is useful in determining mediastinal malignant involvement rapidly and with lesser invasion than with current techniques.
在一项初步研究中，21例患者使用一根45厘米长、22号的针，在半刚性金属套管引导下进行经支气管细针抽吸（TBFNA），该套管通过标准刚性支气管镜插入。共对主隆突（15处）、气管旁（5处）和叶间隆突（13处）病灶进行了33次抽吸。6次抽吸获得了恶性细胞样本，22次抽吸仅呈现正常细胞，5次未获得足够的细胞样本。15例患者接受了手术探查（有或无开胸的纵隔镜检查）。对4例细胞学检查为恶性的病例进行了探查，其中3例的抽吸部位经组织学证实。在其余接受抽吸部位探查的患者中，细胞学检查阴性或细胞学检查不充分的病例未发现肿瘤。TBFNA未出现并发症。我们认为，TBFNA有助于快速确定纵隔恶性受累情况，且与现有技术相比，侵袭性较小。
