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一项关于A型和B型萎缩性胃炎患者对胃抗原的细胞介导免疫的研究。

A study of cell-mediated immunity to gastric antigens in patients with atrophic type A and B gastritis.

作者信息

Kountouras J, Raptopoulou-Gigi M, Goulis G

出版信息

Thymus. 1982 May;4(3):173-7.

PMID:7112638
Abstract

The leucocyte migration in the presence of gastric antigens was studied in 10 patients with type A gastritis, 38 patients with type B gastritis (28 with atrophic and 10 with superficial gastritis) and 10 healthy controls. A positive leucocyte migration was found in a significant proportion of patients with both types of gastritis, whereas no difference between the two types was observed. These results indicate that cellular immunity is implicated in the aetiology of both types of gastritis, is of greater importance than auto-antibody production and is associated with the severity of the atrophic lesion.

摘要

对10例A型胃炎患者、38例B型胃炎患者(28例萎缩性胃炎和10例浅表性胃炎)以及10名健康对照者,研究了在胃抗原存在情况下的白细胞迁移情况。在相当比例的两种类型胃炎患者中均发现白细胞迁移呈阳性,而未观察到两种类型之间存在差异。这些结果表明,细胞免疫与两种类型胃炎的病因学有关,比自身抗体产生更为重要,并且与萎缩性病变的严重程度相关。

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