Manor R S, Yassur Y, Ben-Sira I
Ann Ophthalmol. 1982 Jun;14(6):546-50.
Pupil cycle time was found to correlate with the clinical findings in 24 patients with noncompressive optic nerve pathology, including 11 cases of multiple sclerosis. Furthermore, subclinical multiple sclerosis was detected by the prolongation of pupil cycle time and was confirmed by visual evoked potential analysis. There was a correspondence between dynamics in the clinical findings and the pupil cycle time in two cases of multiple sclerosis that were followed up.
在24例非压迫性视神经病变患者（包括11例多发性硬化症患者）中，发现瞳孔循环时间与临床发现相关。此外，通过瞳孔循环时间延长检测到亚临床多发性硬化症，并通过视觉诱发电位分析得到证实。在随访的2例多发性硬化症患者中，临床发现的动态变化与瞳孔循环时间之间存在对应关系。
