人类线粒体谷氨酸草酰乙酸转氨酶的定位研究。
Mapping studies on human mitochondrial glutamate oxaloacetate transaminase.
作者信息
Jeremiah S J, Povey S, Burley M W, Kielty C, Lee M, Spowart G, Corney G, Cook P J
出版信息
Ann Hum Genet. 1982 May;46(2):145-52. doi: 10.1111/j.1469-1809.1982.tb00705.x.
Abstract
Data from six primary hybrids and twenty-two subclones have confirmed the assignment of the mitochondrial form of glutamate oxaloacetate transaminase to chromosome 16. Family studies have provided independent confirmation of this and have suggested the gene order PGP-16qh-GOT2-HP. These studies were made easier by the development of a new stain for the detection of GOT activity.
摘要
来自六个初级杂种和二十二个亚克隆的数据证实了线粒体形式的谷氨酸草酰乙酸转氨酶定位于16号染色体。家系研究为此提供了独立验证，并提示了基因顺序为PGP - 16qh - GOT2 - HP。一种用于检测GOT活性的新染色方法的开发使这些研究变得更加容易。
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