Burke P A, Callow A D, O'Donnell T F, Kelly J J, Welch H
Arch Surg. 1982 Sep;117(9):1222-7. doi: 10.1001/archsurg.1982.01380330080020.
We assessed the influence of preoperative cardiac risk factors in 57 patients undergoing 70 prophylactic carotid endarterectomies (PCE) and found that: (1) 47 (83%) had at least one cardiac risk factor and (2) nine of 15 deaths occurring in the late follow-up period (40 to 120 months) were due to cardiac causes. Perioperatively, one patient sustained a mild stroke. Although the cumulative stroke-free occurrence rate was kept to less than 6% over the five-year period, cardiac morbidity and mortality greatly influenced the quality of life after PCE. Therefore, PCE is suggested only for patients who have minimal preoperative cardiac risk factors or for those patients whose cardiac risk factors can be improved by medical therapy.
我们评估了57例行70次预防性颈动脉内膜切除术（PCE）患者术前心脏危险因素的影响，发现：（1）47例（83%）至少有一项心脏危险因素；（2）在随访后期（40至120个月）发生的15例死亡中，有9例死于心脏原因。围手术期，1例患者发生轻度卒中。尽管在五年期间无卒中累积发生率保持在6%以下，但心脏发病率和死亡率极大地影响了PCE术后的生活质量。因此，建议仅对术前心脏危险因素极小的患者或心脏危险因素可通过药物治疗改善的患者行PCE。
