Ott D A, Cooley D A, Chapa L, Coelho A
Ann Surg. 1980 Jun;191(6):708-14. doi: 10.1097/00000658-198006000-00008.
A prospective study was undertaken to determine the efficacy of performing carotid endarterectomy without an intraluminal shunt. During a two-year period, 240 patients, ranging in age from 36 to 89 years, underwent 309 consecutive carotid endarterectomies. The indication for operation was transient ischemic attacks in 151 (63%) patients, asymptomatic carotid bruit in 67 (28%), and previous stroke in 22 (9%). Internal shunts were not used in any patients and all arteriotomies were patched with a preclotted knitted Dacron velor patch. Systemic heparinization was used during the procedure. The early postoperative mortality was 0.64% (2/309). Both deaths were caused by myocardial infarction. The incidence of stroke after operation was 1.29% (4/309). Neither carotid clamp time nor the presence of contralateral disease correlated with the occurrence of postoperative stroke. According to results of angiography, 22 patients had total occlusion of the contralateral internal carotid artery with satisfactory intracranial circulation. No postoperative strokes occurred in this subgroup. Results of this study revealed that equally good or superior results may be obtained without a temporary shunt in performing carotid endarterectomy.
进行了一项前瞻性研究,以确定不使用腔内分流器进行颈动脉内膜切除术的疗效。在两年期间,240例年龄在36至89岁之间的患者连续接受了309次颈动脉内膜切除术。手术指征为151例(63%)患者出现短暂性脑缺血发作,67例(28%)患者有无症状颈动脉杂音,22例(9%)患者有既往中风史。所有患者均未使用内分流器,所有动脉切开术均用预凝针织涤纶天鹅绒补片修补。术中使用全身肝素化。术后早期死亡率为0.64%(2/309)。两例死亡均由心肌梗死引起。术后中风发生率为1.29%(4/309)。颈动脉夹闭时间和对侧疾病的存在均与术后中风的发生无关。根据血管造影结果,22例患者对侧颈内动脉完全闭塞,但颅内循环良好。该亚组未发生术后中风。本研究结果表明,在进行颈动脉内膜切除术时不使用临时分流器可能会获得同样好或更好的结果。