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[口服和肌肉注射葡聚糖铁对生长中的雄性犊牛的干预。1. 血液学反应]

[Oral and intramuscular ferridextran intervention in growing male calves. 1. Hematologic reactions].

作者信息

Bünger U, Pongé J, Fiebig U, Kleiner W, Motsch T, Kaphengst P, Furcht G, Schmoldt P

出版信息

Arch Tierernahr. 1982 May;32(5-6):349-68. doi: 10.1080/17450398209421024.

DOI:10.1080/17450398209421024
PMID:7115076
Abstract

195 calves were at random divided into 3 test groups and received oral (200 mg Fe/d) or intramuscular (1.0 and 1.5 g Fe on the 3rd and 36th day of the period of fluid feeding) applications of ferridextrane or no additional quotas of iron (control group) and a limited supply of milk replacer and skim milk as well as ad libitum supply with concentrated feed and dried green fodder during their 56-day period in the range of the rearing farm where the calves receive fluid feed. Iron intervention was carried out without considering the individual iron content of tissue. Its effect was evaluated according to the hemoglobin content (Hb), the hematocrit (Hc) and the mean corpuscular hemoglobin concentration (MCHC) in venous puncture blood. There was no difference between the test groups as to the stabling conditions (affiliation to race and genotype, birth weight, age and live weight resp. at the beginning of the experiment, live weight gain before the beginning of the experiment). In the control group Hb, Hc and MCHC were analogous to previous epidemiologic investigations concerning the anaemia of calves. The ferridextrane interventions carried out resulted in a raised level of Hb and Hc and diminished anaemia frequency as well as the shortened duration of anaemia in this rearing period.

摘要

195头小牛被随机分为3个试验组,分别接受口服(200毫克铁/天)或肌肉注射(在液体喂养期的第3天和第36天分别注射1.0克和1.5克铁)葡聚糖铁,或不额外补充铁(对照组),并在小牛接受液体喂养的饲养场范围内,在56天的时间里,限制代乳品和脱脂牛奶的供应,同时自由采食浓缩饲料和干青饲料。铁干预的实施未考虑组织的个体铁含量。根据静脉穿刺血中的血红蛋白含量(Hb)、血细胞比容(Hc)和平均红细胞血红蛋白浓度(MCHC)评估其效果。试验组在饲养条件(品种和基因型归属、出生体重、实验开始时的年龄和体重、实验开始前的体重增加)方面没有差异。对照组的Hb、Hc和MCHC与先前关于小牛贫血的流行病学调查结果相似。在这个饲养期内,进行的葡聚糖铁干预导致Hb和Hc水平升高,贫血频率降低,贫血持续时间缩短。

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