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A monoclonal antibody to human insulin receptor.

作者信息

Kull F C, Jacobs S, Su Y F, Cuatrecasas P

出版信息

Biochem Biophys Res Commun. 1982 Jun 15;106(3):1019-26. doi: 10.1016/0006-291x(82)91813-7.

DOI:10.1016/0006-291x(82)91813-7

PMID:7115369

Abstract

摘要

相似文献

A monoclonal antibody to human insulin receptor.

Biochem Biophys Res Commun. 1982 Jun 15;106(3):1019-26. doi: 10.1016/0006-291x(82)91813-7.

Murine hybridoma monoclonal antibodies against insulin: cross-reactivity with insulins of three species and blocking of insulin binding to its receptor.

Immunol Lett. 1984;8(5):279-83. doi: 10.1016/0165-2478(84)90009-9.

Insulin-like and insulin-inhibitory effects of monoclonal antibodies for different epitopes on the human insulin receptor.

Biochem J. 1987 Feb 15;242(1):123-9. doi: 10.1042/bj2420123.

Monoclonal antibodies to the human insulin receptor block insulin binding and inhibit insulin action.

Proc Natl Acad Sci U S A. 1982 Dec;79(23):7312-6. doi: 10.1073/pnas.79.23.7312.

Insulin action is blocked by a monoclonal antibody that inhibits the insulin receptor kinase.

Proc Natl Acad Sci U S A. 1986 Jan;83(2):328-32. doi: 10.1073/pnas.83.2.328.

Monoclonal antibodies as probes of the structure and function of insulin receptors.

Biochem Soc Trans. 1987 Feb;15(1):47-51. doi: 10.1042/bst0150047.

Cross-species reactive monoclonal antibodies against the extracellular domains of the insulin receptor and IGF1 receptor.

J Immunol Methods. 2019 Feb;465:20-26. doi: 10.1016/j.jim.2018.11.014. Epub 2018 Nov 27.

Heterogeneity of human liver, muscle, and adipose tissue insulin receptor.

Biochem Biophys Res Commun. 1988 Feb 29;151(1):123-9. doi: 10.1016/0006-291x(88)90567-0.

Monoclonal antibodies reacting with multiple epitopes on the human insulin receptor.

Biochem J. 1986 Apr 1;235(1):199-208. doi: 10.1042/bj2350199.

[Two mouse hybridomas secreting monoclonal antibodies against human liver carcinoma and their antibody specificity].

Shi Yan Sheng Wu Xue Bao. 1985 Jun;18(2):263-70.

引用本文的文献

Characterization of 65 epitope-specific dystrophin monoclonal antibodies in canine and murine models of duchenne muscular dystrophy by immunostaining and western blot.

PLoS One. 2014 Feb 7;9(2):e88280. doi: 10.1371/journal.pone.0088280. eCollection 2014.

Characterization of inhibitory anti-insulin-like growth factor receptor antibodies with different epitope specificity and ligand-blocking properties: implications for mechanism of action in vivo.

J Biol Chem. 2009 Apr 10;284(15):10254-67. doi: 10.1074/jbc.M809709200. Epub 2009 Feb 11.

Cysteine-524 is not the only residue involved in the formation of disulphide-bonded dimers of the insulin receptor.

Biochem J. 1994 Oct 15;303 ( Pt 2)(Pt 2):575-81. doi: 10.1042/bj3030575.

Mutagenic structure/function analysis of the cytoplasmic cysteines of the insulin receptor.

Biochem J. 1995 Mar 15;306 ( Pt 3)(Pt 3):811-20. doi: 10.1042/bj3060811.

Identification and initial characterization of a rat monoclonal antibody reactive with the murine interleukin 2 receptor-ligand complex.

Proc Natl Acad Sci U S A. 1983 Sep;80(18):5694-8. doi: 10.1073/pnas.80.18.5694.

Analysis of the insulin receptor by anti-receptor antibodies and flow cytometry.

Proc Natl Acad Sci U S A. 1984 Dec;81(23):7446-50. doi: 10.1073/pnas.81.23.7446.

Analysis of insulin receptors on human lymphoblastoid cell lines by flow cytometry.

Diabetologia. 1984 Jul;27 Suppl:118-20. doi: 10.1007/BF00275665.

Monoclonal and anti-idiotypic antibodies and the elucidation of receptor structure.

Surv Immunol Res. 1983;2(3):302-5. doi: 10.1007/BF02918438.

Phorbol esters stimulate the phosphorylation of receptors for insulin and somatomedin C.

Proc Natl Acad Sci U S A. 1983 Oct;80(20):6211-3. doi: 10.1073/pnas.80.20.6211.

Monensin blocks the maturation of receptors for insulin and somatomedin C: identification of receptor precursors.

Proc Natl Acad Sci U S A. 1983 Mar;80(5):1228-31. doi: 10.1073/pnas.80.5.1228.

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A monoclonal antibody to human insulin receptor.

作者信息

Kull F C, Jacobs S, Su Y F, Cuatrecasas P

出版信息

Biochem Biophys Res Commun. 1982 Jun 15;106(3):1019-26. doi: 10.1016/0006-291x(82)91813-7.

DOI:10.1016/0006-291x(82)91813-7

PMID:7115369

Abstract

摘要

相似文献

A monoclonal antibody to human insulin receptor.

Biochem Biophys Res Commun. 1982 Jun 15;106(3):1019-26. doi: 10.1016/0006-291x(82)91813-7.

Murine hybridoma monoclonal antibodies against insulin: cross-reactivity with insulins of three species and blocking of insulin binding to its receptor.

Immunol Lett. 1984;8(5):279-83. doi: 10.1016/0165-2478(84)90009-9.

Insulin-like and insulin-inhibitory effects of monoclonal antibodies for different epitopes on the human insulin receptor.

Biochem J. 1987 Feb 15;242(1):123-9. doi: 10.1042/bj2420123.

Monoclonal antibodies to the human insulin receptor block insulin binding and inhibit insulin action.

Proc Natl Acad Sci U S A. 1982 Dec;79(23):7312-6. doi: 10.1073/pnas.79.23.7312.

Insulin action is blocked by a monoclonal antibody that inhibits the insulin receptor kinase.

Proc Natl Acad Sci U S A. 1986 Jan;83(2):328-32. doi: 10.1073/pnas.83.2.328.

Monoclonal antibodies as probes of the structure and function of insulin receptors.

Biochem Soc Trans. 1987 Feb;15(1):47-51. doi: 10.1042/bst0150047.

Cross-species reactive monoclonal antibodies against the extracellular domains of the insulin receptor and IGF1 receptor.

J Immunol Methods. 2019 Feb;465:20-26. doi: 10.1016/j.jim.2018.11.014. Epub 2018 Nov 27.

Heterogeneity of human liver, muscle, and adipose tissue insulin receptor.

Biochem Biophys Res Commun. 1988 Feb 29;151(1):123-9. doi: 10.1016/0006-291x(88)90567-0.

Monoclonal antibodies reacting with multiple epitopes on the human insulin receptor.

Biochem J. 1986 Apr 1;235(1):199-208. doi: 10.1042/bj2350199.

[Two mouse hybridomas secreting monoclonal antibodies against human liver carcinoma and their antibody specificity].

Shi Yan Sheng Wu Xue Bao. 1985 Jun;18(2):263-70.

引用本文的文献

Characterization of 65 epitope-specific dystrophin monoclonal antibodies in canine and murine models of duchenne muscular dystrophy by immunostaining and western blot.

PLoS One. 2014 Feb 7;9(2):e88280. doi: 10.1371/journal.pone.0088280. eCollection 2014.

Characterization of inhibitory anti-insulin-like growth factor receptor antibodies with different epitope specificity and ligand-blocking properties: implications for mechanism of action in vivo.

J Biol Chem. 2009 Apr 10;284(15):10254-67. doi: 10.1074/jbc.M809709200. Epub 2009 Feb 11.

Cysteine-524 is not the only residue involved in the formation of disulphide-bonded dimers of the insulin receptor.

Biochem J. 1994 Oct 15;303 ( Pt 2)(Pt 2):575-81. doi: 10.1042/bj3030575.

Mutagenic structure/function analysis of the cytoplasmic cysteines of the insulin receptor.

Biochem J. 1995 Mar 15;306 ( Pt 3)(Pt 3):811-20. doi: 10.1042/bj3060811.

Identification and initial characterization of a rat monoclonal antibody reactive with the murine interleukin 2 receptor-ligand complex.

Proc Natl Acad Sci U S A. 1983 Sep;80(18):5694-8. doi: 10.1073/pnas.80.18.5694.

Analysis of the insulin receptor by anti-receptor antibodies and flow cytometry.

Proc Natl Acad Sci U S A. 1984 Dec;81(23):7446-50. doi: 10.1073/pnas.81.23.7446.

Analysis of insulin receptors on human lymphoblastoid cell lines by flow cytometry.

Diabetologia. 1984 Jul;27 Suppl:118-20. doi: 10.1007/BF00275665.

Monoclonal and anti-idiotypic antibodies and the elucidation of receptor structure.

Surv Immunol Res. 1983;2(3):302-5. doi: 10.1007/BF02918438.

Phorbol esters stimulate the phosphorylation of receptors for insulin and somatomedin C.

Proc Natl Acad Sci U S A. 1983 Oct;80(20):6211-3. doi: 10.1073/pnas.80.20.6211.

Monensin blocks the maturation of receptors for insulin and somatomedin C: identification of receptor precursors.

Proc Natl Acad Sci U S A. 1983 Mar;80(5):1228-31. doi: 10.1073/pnas.80.5.1228.