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A monoclonal antibody to human insulin receptor.

作者信息

Kull F C, Jacobs S, Su Y F, Cuatrecasas P

出版信息

Biochem Biophys Res Commun. 1982 Jun 15;106(3):1019-26. doi: 10.1016/0006-291x(82)91813-7.

DOI:10.1016/0006-291x(82)91813-7
PMID:7115369
Abstract
摘要

相似文献

1
A monoclonal antibody to human insulin receptor.一种针对人胰岛素受体的单克隆抗体。
Biochem Biophys Res Commun. 1982 Jun 15;106(3):1019-26. doi: 10.1016/0006-291x(82)91813-7.
2
Murine hybridoma monoclonal antibodies against insulin: cross-reactivity with insulins of three species and blocking of insulin binding to its receptor.抗胰岛素的小鼠杂交瘤单克隆抗体:与三种物种胰岛素的交叉反应性及对胰岛素与其受体结合的阻断作用
Immunol Lett. 1984;8(5):279-83. doi: 10.1016/0165-2478(84)90009-9.
3
Insulin-like and insulin-inhibitory effects of monoclonal antibodies for different epitopes on the human insulin receptor.针对人胰岛素受体不同表位的单克隆抗体的胰岛素样和胰岛素抑制作用。
Biochem J. 1987 Feb 15;242(1):123-9. doi: 10.1042/bj2420123.
4
Monoclonal antibodies to the human insulin receptor block insulin binding and inhibit insulin action.针对人胰岛素受体的单克隆抗体可阻断胰岛素结合并抑制胰岛素作用。
Proc Natl Acad Sci U S A. 1982 Dec;79(23):7312-6. doi: 10.1073/pnas.79.23.7312.
5
Insulin action is blocked by a monoclonal antibody that inhibits the insulin receptor kinase.胰岛素的作用被一种抑制胰岛素受体激酶的单克隆抗体所阻断。
Proc Natl Acad Sci U S A. 1986 Jan;83(2):328-32. doi: 10.1073/pnas.83.2.328.
6
Monoclonal antibodies as probes of the structure and function of insulin receptors.单克隆抗体作为胰岛素受体结构与功能的探针
Biochem Soc Trans. 1987 Feb;15(1):47-51. doi: 10.1042/bst0150047.
7
Cross-species reactive monoclonal antibodies against the extracellular domains of the insulin receptor and IGF1 receptor.针对胰岛素受体和 IGF1 受体胞外结构域的种属交叉反应性单克隆抗体。
J Immunol Methods. 2019 Feb;465:20-26. doi: 10.1016/j.jim.2018.11.014. Epub 2018 Nov 27.
8
Heterogeneity of human liver, muscle, and adipose tissue insulin receptor.
Biochem Biophys Res Commun. 1988 Feb 29;151(1):123-9. doi: 10.1016/0006-291x(88)90567-0.
9
Monoclonal antibodies reacting with multiple epitopes on the human insulin receptor.与人胰岛素受体上多个表位发生反应的单克隆抗体。
Biochem J. 1986 Apr 1;235(1):199-208. doi: 10.1042/bj2350199.
10
[Two mouse hybridomas secreting monoclonal antibodies against human liver carcinoma and their antibody specificity].[两种分泌抗人肝癌单克隆抗体的小鼠杂交瘤及其抗体特异性]
Shi Yan Sheng Wu Xue Bao. 1985 Jun;18(2):263-70.

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1
Characterization of 65 epitope-specific dystrophin monoclonal antibodies in canine and murine models of duchenne muscular dystrophy by immunostaining and western blot.通过免疫染色和蛋白质印迹法对杜兴氏肌营养不良症犬类和小鼠模型中65种表位特异性抗肌萎缩蛋白单克隆抗体进行表征。
PLoS One. 2014 Feb 7;9(2):e88280. doi: 10.1371/journal.pone.0088280. eCollection 2014.
2
Characterization of inhibitory anti-insulin-like growth factor receptor antibodies with different epitope specificity and ligand-blocking properties: implications for mechanism of action in vivo.具有不同表位特异性和配体阻断特性的抑制性抗胰岛素样生长因子受体抗体的表征:对体内作用机制的启示
J Biol Chem. 2009 Apr 10;284(15):10254-67. doi: 10.1074/jbc.M809709200. Epub 2009 Feb 11.
3
Cysteine-524 is not the only residue involved in the formation of disulphide-bonded dimers of the insulin receptor.半胱氨酸524并非参与胰岛素受体二硫键连接二聚体形成的唯一残基。
Biochem J. 1994 Oct 15;303 ( Pt 2)(Pt 2):575-81. doi: 10.1042/bj3030575.
4
Mutagenic structure/function analysis of the cytoplasmic cysteines of the insulin receptor.胰岛素受体胞质半胱氨酸的诱变结构/功能分析
Biochem J. 1995 Mar 15;306 ( Pt 3)(Pt 3):811-20. doi: 10.1042/bj3060811.
5
Identification and initial characterization of a rat monoclonal antibody reactive with the murine interleukin 2 receptor-ligand complex.一种与小鼠白细胞介素2受体-配体复合物反应的大鼠单克隆抗体的鉴定及初步表征。
Proc Natl Acad Sci U S A. 1983 Sep;80(18):5694-8. doi: 10.1073/pnas.80.18.5694.
6
Analysis of the insulin receptor by anti-receptor antibodies and flow cytometry.利用抗受体抗体和流式细胞术分析胰岛素受体。
Proc Natl Acad Sci U S A. 1984 Dec;81(23):7446-50. doi: 10.1073/pnas.81.23.7446.
7
Analysis of insulin receptors on human lymphoblastoid cell lines by flow cytometry.
Diabetologia. 1984 Jul;27 Suppl:118-20. doi: 10.1007/BF00275665.
8
Monoclonal and anti-idiotypic antibodies and the elucidation of receptor structure.
Surv Immunol Res. 1983;2(3):302-5. doi: 10.1007/BF02918438.
9
Phorbol esters stimulate the phosphorylation of receptors for insulin and somatomedin C.佛波酯可刺激胰岛素和生长调节素C受体的磷酸化。
Proc Natl Acad Sci U S A. 1983 Oct;80(20):6211-3. doi: 10.1073/pnas.80.20.6211.
10
Monensin blocks the maturation of receptors for insulin and somatomedin C: identification of receptor precursors.莫能菌素阻断胰岛素和生长调节素C受体的成熟:受体前体的鉴定。
Proc Natl Acad Sci U S A. 1983 Mar;80(5):1228-31. doi: 10.1073/pnas.80.5.1228.