Mabe H, Umemura S, Yoshida T, Iwayama K, Iwama M, Nagai H
No To Shinkei. 1982 Jun;34(6):585-9.
Varying degrees of cerebral ischemia were produced in adult Wistar rats by clipping of bilateral common carotid arteries with or without induced hypotension. Local cerebral blood flow was measured from bilateral caudate nuclei and parietal cortices using the hydrogen clearance method. EEG was recorded from the same electrode as used for the hydrogen clearance method. The delta power of EEG increased along with decreasing local cerebral blood flow. There was an inverse correlation between the delta power of EEG and local CBF values, ranging from normal to extremely low (10 ml/100 g/min). When local CBF was reduced below 6-8 ml/100 g/min, EEG became isoelectric. Continuous EEG recording might contribute to predict rCBF value in the ischemic lesion.
通过夹闭双侧颈总动脉(有无诱导性低血压)在成年Wistar大鼠中产生不同程度的脑缺血。使用氢清除法从双侧尾状核和顶叶皮质测量局部脑血流量。脑电图(EEG)记录使用与氢清除法相同的电极。EEG的δ波功率随着局部脑血流量的减少而增加。EEG的δ波功率与局部脑血流量值之间存在负相关,范围从正常到极低(10毫升/100克/分钟)。当局部脑血流量降至6 - 8毫升/100克/分钟以下时,EEG变为等电位。持续的EEG记录可能有助于预测缺血性病变中的局部脑血流量值。