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[Effect of bivalent copper ions on the catalytic properties of bovine liver glutamate dehydrogenase].

作者信息

Agadzhanian S A, Karabashian L V

出版信息

Biokhimiia. 1982 Jun;47(6):1022-6.

PMID:7115801
Abstract

The effects of bivalent copper ions on the activity of bovine liver glutamate dehydrogenase (L-glutamate NAD (P) oxidoreductase, EC 1.4.1.3) were studied. Cu2+ effectively interacts with the enzyme; this interaction is accompanied by a loss of the enzyme activity in the reaction of reductive amination of alpha-ketoglutarate. The data obtained are indicative of a similar type of the enzyme inhibition by GTP and copper ions.

摘要

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