Dubey J P, Stromberg P C, Toussant M J, Hoover E A, Pechman R D
J Am Vet Med Assoc. 1978 Sep 15;173(6):734-42.
Twenty-eight specific-pathogen-free cats were inoculated with 14 to 50 metacercariae of Paragonimus kellicotti obtained from the hearts of naturally infected crayfish. Young flukes excysted in the intestine of cats and appeared in the peritoneal cavity from 1 to 14 days after inoculation (DAI) and in the pleural cavity from 5 to 23 DAI. Flukes penetrated the pulmonary parenchyma and formed hemorrhagic subpleural lesions within 5 weeks after inoculation. Marked eosinophilia developed between 2 and 12 weeks after inoculation. Fluke-containing pulmonary lesions were detected by radiography 3 to 4 weeks after inoculation. Lesions developed most frequently in the right caudal lung lobe. Clinical signs were mild and did not appear until 4 weeks after inoculation. Thereafter, cats appeared dull and coughed intermittently. One cat became dyspneic due to pneumothorax. Paragonimus eggs were first detected at the 34th DAI, using a fecal sedimentation technique.
将28只无特定病原体的猫接种从自然感染小龙虾心脏获取的14至50个凯氏并殖吸虫囊蚴。童虫在猫的肠道内脱囊，接种后1至14天出现在腹腔，5至23天出现在胸腔。接种后5周内，吸虫穿透肺实质并形成胸膜下出血性病变。接种后2至12周出现明显的嗜酸性粒细胞增多。接种后3至4周通过X线摄影检测到含吸虫的肺部病变。病变最常发生在右尾叶肺。临床症状较轻，接种后4周才出现。此后，猫显得迟钝并间歇性咳嗽。一只猫因气胸出现呼吸困难。使用粪便沉淀技术在接种后第34天首次检测到并殖吸虫卵。
