Kurtzberg D, Vaughan H G
Brain Res. 1982 Jul 8;243(1):1-9. doi: 10.1016/0006-8993(82)91115-5.
The topography of human brain potentials preceding self-initiated saccadic eye movements was compared with those preceding visually triggered saccades to examine differences in presaccadic activity under different programming requirements. A slow negative shift beginning approximately 650 ms before eye movement and largest in amplitude over the frontal region was recorded only in the self-initiated condition. This potential presumably reflects preparatory activity occurring predominantly within the frontal eye fields. A ramp-like positivity preceding eye movements by 100-250 ms and a sharp positive potential peaking 10-40 ms before saccades were recorded under both conditions. These potentials were of maximum amplitude over the parietal region. In order to examine the extent to which presaccadic enhancement of parietal activity was related to executive or to attentional mechanisms, the presaccadic visual evoked potential components were compared with activity at the same latency when stimuli were counted without saccades or were ignored. Enhancement of parietal potentials was seen both with counting and with saccades, but was greater in the eye movement condition. Occipital enhancement predominated with counting and parietal enhancement with saccades. These findings suggest that attentional and command mechanisms contribute distinct complementary increments in posterior cortical presaccadic activity associated with visually triggered saccades.
将自主发起的眼球跳动之前的人脑电位地形图与视觉触发的眼球跳动之前的地形图进行比较，以检查不同编程要求下扫视前活动的差异。仅在自主发起的情况下记录到一个缓慢的负向偏移，该偏移在眼球运动前约650毫秒开始，在额叶区域幅度最大。这种电位可能反映了主要在额叶眼区发生的准备活动。在两种情况下均记录到眼球运动前100 - 250毫秒出现的斜坡样正向电位以及扫视前10 - 40毫秒达到峰值的尖锐正向电位。这些电位在顶叶区域幅度最大。为了检查顶叶活动的扫视前增强与执行机制或注意力机制的相关程度，将扫视前视觉诱发电位成分与在不进行扫视或忽略刺激时相同潜伏期的活动进行比较。在计数和扫视时均可见顶叶电位增强，但在眼球运动条件下增强更大。计数时枕叶增强为主，扫视时顶叶增强为主。这些发现表明，注意力和指令机制在与视觉触发扫视相关的后皮质扫视前活动中贡献了不同的互补性增量。
