[New data on the mechanisms of glucose transport in the small intestine based on an analysis of the role of serous-mucous flows].

The transport of glucose, other monosaccharides and disaccharides in the rat small intestine has been studied under the condition of a predominance of serosal-to-mucosal (SM) flows over mucosal-to-serosal (MS) ones. A dependence has been found of the efflux of glucose into the serosal solution on the duration of incubation, starting glucose concentration in the serosal solution, intestinal segment under study (proximal-distal gradient), action of glucose transport inhibitors (phlorizin, absence of Na+ in the incubation medium, anoxia) and temperature. In this paper, the hypothesis on entero-hematic circulation has been proposed, according to which recycling of glucose is one of the important manifestations of processes of microcirculation of substances between blood and the intestine.