Vidal M A, Bernabeu C, Conde F P
Immunol Lett. 1982 Jun;4(6):311-5. doi: 10.1016/0165-2478(82)90058-x.
Human immunoglobulin M binds to protein A-bearing Staphylococcus aureus. This binding is specific for protein A since it is inhibited by rabbit Fab against Staphylococcal protein A. Analysis of the IgM binding data gives an apparent KD of 0.94 nM and a maximum capacity of approximately 2 X 10(3) binding sites of IgM per bacteria.
人免疫球蛋白M与携带蛋白A的金黄色葡萄球菌结合。这种结合对蛋白A具有特异性,因为它可被抗葡萄球菌蛋白A的兔Fab片段所抑制。对免疫球蛋白M结合数据的分析得出,其表观解离常数(KD)为0.94纳摩尔,每个细菌上免疫球蛋白M的最大结合容量约为2×10³个结合位点。