共培养对中国仓鼠细胞中自发和诱导的姐妹染色单体交换水平的影响。
Effect of cocultivation on the levels of spontaneous and induced sister chromatid exchanges in Chinese hamster cells.
作者信息
Rainaldi G, Luccini F, Mariani T
出版信息
J Cell Physiol. 1982 Aug;112(2):281-3. doi: 10.1002/jcp.1041120218.
PMID:7119024
Abstract
The level of sister chromatid exchanges, both spontaneous and induced by UV light or ethylmethanesulphonate (EMS), in Chinese hamster V79/AP4 cell line, is partially reduced upon cocultivation with human cells. Normal and xeroderma pigmentosum (XP) cells are equally effective. On the basis of these observations, cocultivation may represent a good tool for investigating the SCE's formation processes.
摘要
在中国仓鼠V79/AP4细胞系中，姐妹染色单体交换水平，包括自发的以及紫外线或甲磺酸乙酯（EMS）诱导的，在与人细胞共培养时会部分降低。正常细胞和着色性干皮病（XP）细胞的效果相同。基于这些观察结果，共培养可能是研究姐妹染色单体交换形成过程的一个好工具。
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