Raghunathan R, Miller M E, Everett S, Leake R D
J Clin Immunol. 1982 Jul;2(3):242-5. doi: 10.1007/BF00915228.
Cross-sectional and limited sequential studies of neutrophil and monocyte chemotaxis were done using cells isolated from cord blood and peripheral blood of 2- to 6-day-old neonates and infants at 4 and 6 months of age. These studies show that cord blood phagocyte chemotaxis is comparable to adult values, whereas phagocyte chemotaxis at 2-6 days of age is significantly lower than adult (P less than 0.01) or cord (P less 0.01) chemotaxis values. At 6 months of age, phagocyte chemotaxis is still low compared to adult values (P less than 0.01).
利用从2至6日龄新生儿以及4个月和6个月大婴儿的脐带血和外周血中分离出的细胞，进行了中性粒细胞和单核细胞趋化性的横断面和有限序列研究。这些研究表明，脐带血吞噬细胞趋化性与成人水平相当，而2至6日龄时的吞噬细胞趋化性显著低于成人（P小于0.01）或脐带（P小于0.01）趋化性值。在6个月大时，与成人值相比，吞噬细胞趋化性仍然较低（P小于0.01）。
