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豚鼠肠系膜下神经节连接性的结构研究。

Structural studies on the connectivity of the inferior mesenteric ganglion of the guinea pig.

作者信息

Dalsgaard C J, Elfvin L G

出版信息

J Auton Nerv Syst. 1982 May;5(3):265-78. doi: 10.1016/0165-1838(82)90070-4.

DOI:10.1016/0165-1838(82)90070-4
PMID:7119357
Abstract

After injection of horseradish peroxidase (HRP) into the inferior mesenteric ganglion (IMG) of the guinea pig, labeled cell bodies were found in the solar plexus ganglia, the ganglia of the pelvic plexus and in the nodose ganglia as well as in the spinal cord and dorsal root ganglia at the T13-L4 levels. By using the fluorescent tracer True blue, labeled cell bodies could also be detected in the myenteric and submucosa ganglia of the distal colon. Application and uptake of HRP by the colonic nerves resulted in labeling of cell bodies in the dorsal root ganglia, the IMG and in the solar plexus ganglion complex indicating that the latter neurons send their axons in the intermesenteric nerve through the IMG to continue in the colonic nerves to the distal colon. When HRP was applied and diffused into the hypogastric nerves labeled cell bodies were seen in the IMG, the dorsal root ganglia and in the preganglionic nuclei of the lumbar spinal cord with 50% of the labeled neurons located dorsal and dorsolateral to the central canal. The finding of such a diversity in the nerve supply to the IMG, supports the view that the ganglion plays an important role in the integration of visceral reflexes.

摘要

将辣根过氧化物酶(HRP)注射到豚鼠肠系膜下神经节(IMG)后,在腹腔神经节、盆腔神经节、结状神经节以及T13 - L4水平的脊髓和背根神经节中发现了标记的细胞体。通过使用荧光示踪剂真蓝,在远端结肠的肌间神经节和黏膜下神经节中也能检测到标记的细胞体。结肠神经对HRP的应用和摄取导致背根神经节、IMG和腹腔神经节复合体中的细胞体被标记,这表明后一组神经元通过IMG将其轴突发送到肠系膜间神经,继续通过结肠神经到达远端结肠。当HRP应用并扩散到腹下神经时,在IMG、背根神经节和腰脊髓的节前核中可见标记的细胞体,其中50%的标记神经元位于中央管的背侧和背外侧。IMG神经供应存在如此多样性的发现,支持了该神经节在内脏反射整合中起重要作用的观点。

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