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患有繁茂头巾瘤患者腮腺的多中心性皮肤型圆柱瘤

Multicentric dermal-type cylindromas of the parotid glands in a patient with florid turban tumor.

作者信息

Reingold I M, Keasbey L E, Graham J H

出版信息

Cancer. 1977 Oct;40(4):1702-10. doi: 10.1002/1097-0142(197710)40:4<1702::aid-cncr2820400446>3.0.co;2-a.

DOI:10.1002/1097-0142(197710)40:4<1702::aid-cncr2820400446>3.0.co;2-a
PMID:71195
Abstract

Dermal-type cylindromas of parotid glands in a patient with turban tumor, and various adnexal tumors, represent a rare diathesis, apparently not reported previously. A Caucasian man, born in 1916, had a scalpectomy for turban tumor in 1957. In 1957, 1960, and 1974, dermal type cylindromas were excised from portions of both parotid glands, developing from intercalated and striated ducts; they were considered benign, based on long term followup. Adrexal tumors included multiple dermal cylindromas, trichoepitheliomas, eccrine spiradenomas, and Bowen's disease, and occurred on almost all skin surfaces. In November, 1976, a portion of a right parotidectomy included a 3.5 X 3-cm malignant tumor having the characteristics of an invasive poorly differentiated spindle cell epidermoid carcinoma, which showed no evidence of originating from a malignant basal cell tumor. Several encapsulated and developing benign basal cell tumors were included in the specimen. Dermal-type cyclindromas of the parotid gland are considered to be a variant of basal cell ademona, or monomorphic adenoma, basal cell type, since they consist of similar cell components, although of somewhat different arrangement and with prominent focal deposition of hyaline. Dermal-type cylindromas should be excised conservatively as they appear. They must be differentiated from adenoid cystic carcinoma, which is an infiltrating neoplasm and requires a radical surgical approach.

摘要

一名患有头巾瘤及多种附属器肿瘤的患者,其腮腺出现皮肤型圆柱瘤,这代表一种罕见的素质,此前显然未有报道。一名1916年出生的白种男性,于1957年因头巾瘤接受了头皮切除术。1957年、1960年和1974年,从双侧腮腺的部分区域切除了皮肤型圆柱瘤,这些肿瘤由闰管和纹状管发展而来;基于长期随访,它们被认为是良性的。附属器肿瘤包括多发性皮肤圆柱瘤、毛发上皮瘤、小汗腺螺旋腺瘤和鲍温病,几乎出现在所有皮肤表面。1976年11月,右侧腮腺部分切除术切除的标本中包含一个3.5×3厘米的恶性肿瘤,其具有浸润性低分化梭形细胞表皮样癌的特征,未显示出源自恶性基底细胞瘤的证据。标本中还包括几个包膜完整且正在发展的良性基底细胞瘤。腮腺皮肤型圆柱瘤被认为是基底细胞腺瘤或单形性腺瘤基底细胞型的一种变体,因为它们由相似的细胞成分组成,尽管排列有所不同且有明显的透明质局灶性沉积。皮肤型圆柱瘤一旦出现应行保守切除。它们必须与腺样囊性癌相鉴别,腺样囊性癌是一种浸润性肿瘤,需要采取根治性手术方法。

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Multicentric dermal-type cylindromas of the parotid glands in a patient with florid turban tumor.患有繁茂头巾瘤患者腮腺的多中心性皮肤型圆柱瘤
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Membranous basal cell adenoma of the parotid gland. Malignant transformation in a patient with multiple dermal cylindromas.腮腺膜性基底细胞腺瘤。一名患有多发性皮肤圆柱瘤的患者发生恶性转化。
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Basal cell adenocarcinoma and Basal cell adenoma of the salivary glands: a clinicopathological review of seventy tumors with comparison of morphologic features and growth control indices.
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Dermal eccrine cylindromatosis.皮肤小汗腺圆柱瘤病
J Med Genet. 1994 Apr;31(4):321-4. doi: 10.1136/jmg.31.4.321.
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Multifocal dermal-type basal cell adenomas of parotid glands with co-existing dermal cylindromas.腮腺多灶性皮肤型基底细胞腺瘤伴发皮肤圆柱瘤
Virchows Arch A Pathol Anat Histopathol. 1984;403(1):95-102. doi: 10.1007/BF00689342.