Patterson V H, Kaiser K K, Brooke M H
J Neurol Neurosurg Psychiatry. 1982 Jun;45(6):552-3. doi: 10.1136/jnnp.45.6.552.
Plasma hypoxanthine was measured in three normal subjects during aerobic forearm exercise. The comparative increase of hypoxanthine greatly exceeded that of ammonia or lactate. It is proposed that hypoxanthine production reflects ATP breakdown in muscle. The test may prove useful in the investigation of patients with metabolic muscle disease.
在三名正常受试者进行有氧前臂运动期间测量了血浆次黄嘌呤。次黄嘌呤的相对增加大大超过了氨或乳酸的增加。有人提出,次黄嘌呤的产生反映了肌肉中ATP的分解。该测试可能对代谢性肌肉疾病患者的调查有用。