Miller J M, Keane M W, Horger E O
J Reprod Med. 1982 Jun;27(6):348-51.
Intravenous magnesium sulfate and terbutaline were compared as treatments for premature labor. A successful treatment was the arrest of labor for 24 hours. Early treatment was essential for successful management of premature labor. In this study, magnesium sulfate and terbutaline were equally effective in controlling premature labor. Whereas terbutaline was associated with significant alterations in diastolic blood pressure, maternal pulse, fetal heart rate and potassium concentration, magnesium sulfate was not. Magnesium sulfate holds promise as a tocolytic agent, and further clinical study of it is warranted.
对静脉注射硫酸镁和特布他林治疗早产进行了比较。成功的治疗是使分娩停止24小时。早期治疗对于早产的成功处理至关重要。在本研究中，硫酸镁和特布他林在控制早产方面同样有效。然而，特布他林与舒张压、母体脉搏、胎儿心率和钾浓度的显著变化相关，而硫酸镁则没有。硫酸镁有望成为一种宫缩抑制剂，有必要对其进行进一步的临床研究。
